Conformed by Luján de Cuyo y Maipú and a few districts of Guaymallén, Las Heras and Godoy Cruz. This region has over 25.000 hectares, watered by Mendoza River, characteristics of the ground and weather wich the firsts wine makers loved. It is located in the foothills and extends from the 1,060 meters to the 650 meters of altitude. The average annual temperature is 15º C and the thermal amplitude is one of the characteristics that give personality to the varieties best suited to the region: Malbec, Cabernet Sauvignon, Tempranillo, Bonarda, Syrah and Sangiovese (among red wines).
It is made up of the departments of San Martin, Junín, Santa Rosa, La Paz and Rivadavia, and represent the largest wine region in the country; Has about seventy thousand hectares dedicated to this activity. In addition, the olive growing, fruit growing and beekeeping activities have been developed. It is a plain area receiving waters of Tunuyán River and part of Mendoza River. Its winemaking in "el llano" is settled between 750 meters, in the highest areas, and 650 meters above sea level. This region has a warm weather and a regime superior to 2,200 hours of sun in the period of 210 days, favorable for the vegetative development, which allows the optimal maturation of the cultivated varieties. Its soils are of wind origin, rich in potassium. There are some plots of saline soils.
The region is made up of the departments of Tunuyán, Tupungato and San Carlos, in the Center-West of Mendoza, between 33º5 'and 35º south latitude. The altitude of the vineyards of the Uco Valley settle down from 1500 meters in the Old Tupungato to 860 meters above sea level in the town of Tunuyán. Its climate is temperates with harsh winters and warm summers and cool nights. The average annual temperature is 14.2º C. It has about 13,000 hectares of vineyards, at the foot of the "Cordillera de los Andes". The region is characterized by its ability to produce quality raw material, both for the production of white and red wines. The good acidity achieved by the grapes allows the wines of the Uco Valley to be suitable for prolonged aging.